Mitochondrial Metabolism in Models of Lung Aging

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Job Description

Job Description

Join our amazing Lab Team in the Division of Pulmonary Medicine in the R01-funded laboratory of Corrine Kliment, MD, Ph.D. We are seeking a highly self-motivated candidate with a strong background in mitochondrial metabolism, epithelial biology, molecular biology, or a related field. The successful candidate will study how mitochondrial proteins, specifically adenine nucleotide translocase or ANT, regulate epithelial function in models of lung disease including chronic obstructive lung disease (COPD) with a focus on cellular senescence pathways. The project will initially focus on the establishment of in vitro primary cell culture models (3D organoids and precision-cut lung slices) and the use of in vivo mouse models of COPD that have been previously established. Salary will be commensurate with experience. Our lab is supportive, productive, and committed to the career development of basic and translational scientists.

Responsibilities

The candidate will be expected to plan, execute and analyze experiments spanning from primary human cell culture to animal studies.

Job Requirements

Successful applicants will hold a Ph.D., MD, or MD/Ph.D. Strong written and verbal communication skills in English are essential.

Skills and experience in investigating aspects of epithelial cell function, mitochondrial biology, confocal microscopy, and mouse models of lung disease are strongly encouraged.