Nuno Raimundo

Job Description

My major focus of research is to understand how mitochondria communicate with the rest of the cell, both in physiological conditions and in pathology. We employ multiple -omics approaches, including genomics image-based screens, transcriptomics and proteomics, to identify signaling mechanisms underlying metabolic defects. Our work is mostly focused on the mitochondria-lysosome network and its implications for cellular proliferation, autophagy and death, as well as organism-level processes such as aging.

Specialties: Mitochondrial physiology and pathology, lysosome, autophagy, energy metabolism, cellular signaling, AMPK, mTORC1, redox homeostasis, cell biology, live imaging, molecular biology, transcriptome analysis, in silico promoter analysis, Q-PCR, genomic screening, CRISPR, shRNA, siRNA, in vivo, peroxisomes, autophagy, functional assay.